Laforin/EPM2A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24474

Novus Biologicals, part of Bio-Techne
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NBP2-24474
NBP2-24474SS
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Key Product Details

Species Reactivity

Validated:

Human, Bovine

Cited:

Bovine

Predicted:

Canine (100%), Chicken (93%), Chimpanzee (100%), Equine (100%), Mouse (100%), Opossum (93%), Primate (93%), Rat (100%), Rhesus Macaque (93%), Xenopus (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Laforin/EPM2A Antibodies »

Product Specifications

Immunogen

A portion of amino acids 80-130 of human Laforin/EPM2A was used as the immunogen for the antibody.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Zebrafish (87%). Bovine data from PMID: 32146261.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Laforin/EPM2A Antibody

Western Blot: Laforin/EPM2A Antibody [NBP2-24474]

Western Blot: Laforin/EPM2A Antibody [NBP2-24474]

Western Blot: Laforin/EPM2A Antibody [NBP2-24474] - Analysis of EPM2A in human heart lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse heart and 4) rat heart lysate using this antibody. 25 ug/ml, 0.5 ug/ml and 0.5 ug/ml, respectively.
Immunohistochemistry-Paraffin: Laforin/EPM2A Antibody [NBP2-24474]

Immunohistochemistry-Paraffin: Laforin/EPM2A Antibody [NBP2-24474]

Immunohistochemistry-Paraffin: Laforin/EPM2A Antibody [NBP2-24474] - Formalin-fixed, paraffin-embedded human heart stained with EPM2A antibody at 10 ug/ml. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

Applications for Laforin/EPM2A Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

0.25-0.50 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Laforin/EPM2A

EPM2A encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Alternate Names

EPM2A, LAFPTPase, LDE, MELF

Gene Symbol

EPM2A

UniProt

Q6VVB1 (Human)

Additional Laforin/EPM2A Products

Product Documents for Laforin/EPM2A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Laforin/EPM2A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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