LAIR1 Antibody (NKTA255)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62214

Clone NKTA255 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # NKTA255

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all LAIR1 Antibodies »

Product Specifications

Immunogen

Activated NK cells and CD3- thymocytes

Specificity

The mouse monoclonal antibody NKTA255 recognizes CD305 / LAIR1, a 40 kDa type I transmembrane glycoprotein expressed on NK, T, and B cells, monocytes, dendritic cells, eosinophils, basophils, mast cells, CD34+ hematopoietic progenitor cells and thymocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for LAIR1 Antibody (NKTA255)

Flow (Cell Surface): LAIR1 Antibody (NKTA255) [NBP2-62214]

Flow (Cell Surface): LAIR1 Antibody (NKTA255) [NBP2-62214]

Flow (Cell Surface): LAIR1 Antibody (NKTA255) [NBP2-62214] - Surface staining of CD305 / LAIR-1 in human peripheral blood with anti-CD305 (NKTA255) PerCP-CyTM5.5.
Flow (Cell Surface): LAIR1 Antibody (NKTA255) [NBP2-62214]

Flow (Cell Surface): LAIR1 Antibody (NKTA255) [NBP2-62214]

Flow (Cell Surface): LAIR1 Antibody (NKTA255) [NBP2-62214] - Surface staining of CD305 / LAIR-1 in human peripheral blood (lymphocyte gate) with anti-CD305 (NKTA255) PE.
LAIR1 Antibody (NKTA255) Flow Cytometry: LAIR1 Antibody (NKTA255) [NBP2-62214]

Flow Cytometry: LAIR1 Antibody (NKTA255) [NBP2-62214]

Surface staining of human lymphocytes stained using anti-human CD305 (NKTA255) purified antibody (concentration in sample 2 ug/ml, GAM APC) and anti-human CD19 (LT19) PE antibody (20 μl reagent / 100 μl of peripheral whole blood).

Applications for LAIR1 Antibody (NKTA255)

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000

Reviewed Applications

Read 1 review rated 5 using NBP2-62214 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: LAIR1

LAIR1 is a transmembrane glycoprotein(approx. 32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. This clone is reported to inhibit NK cell triggering via CD16 molecules.

Long Name

Leukocyte-associated Ig-like Receptor 1

Alternate Names

CD305, HLAIR1, LAIR-1

Gene Symbol

LAIR1

Additional LAIR1 Products

Product Documents for LAIR1 Antibody (NKTA255)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LAIR1 Antibody (NKTA255)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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