LAIR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-68845

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-68845
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all LAIR1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-NDTEDVSQASPSE corresponding to internal region according to NP_002278.1, NP_068352.1.

Epitope

C-NDTEDVSQASPSE

Specificity

This antibody is expected to recognize both isoforms (NP_002278.1; NP_068352.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for LAIR1 Antibody

Western Blot: LAIR1 Antibody [NBP1-68845]

Western Blot: LAIR1 Antibody [NBP1-68845]

Western Blot: LAIR1 Antibody [NBP1-68845] - Analysis of LAIR1 in Human Lymph Node lysate (35ug protein in RIPA buffer) using NBP1-68845 at 2ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: LAIR1 Antibody [NBP1-68845]

Immunohistochemistry-Paraffin: LAIR1 Antibody [NBP1-68845]

Immunohistochemistry-Paraffin: LAIR1 Antibody [NBP1-68845] - 3.75ug/ml staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for LAIR1 Antibody

Application
Recommended Usage

Immunohistochemistry

1-3ug/ml

Peptide ELISA

Detection limit 1:1000

Western Blot

1:1000
Application Notes
Western blot: Approx 28kDa band observed in Human Lymph Node lysates (calculated MW of 29.8kDa according to NP_068352.1). Primary incubation was 1 hour
IHC: Paraffin embedded Human Tonsil.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: LAIR1

CD305 or Leukocyte-associated Ig-like receptor-1 (LAIR-1) is a 46 kD cell surface molecule that functions as an inhibitory collagen-receptor on the majority of cells of the immune system. The mouse LAIR-1 molecule is expressed primarily on monocytes/macrophages and also on T cells, NK cells and dendritic cells. Unlike human B cells , mouse B cells do not express LAIR-1. The cytoplasmic tail of mouse LAIR-1 can be phosphorylated leading to the recruitment of SH2-containing tyrosine phosphatase(SHP)-2 and C-terminal Src kinase.

Long Name

Leukocyte-associated Ig-like Receptor 1

Alternate Names

CD305, HLAIR1, LAIR-1

Entrez Gene IDs

3903 (Human)

Gene Symbol

LAIR1

UniProt

NP_002278.1 (Human)

Additional LAIR1 Products

Product Documents for LAIR1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LAIR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.