Lambda5/IGLL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56431

Novus Biologicals, part of Bio-Techne
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NBP2-56431
NBP2-56431-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Lambda5/IGLL1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: GFQSKHNSVTHVFGSGTQLTVLSQPK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Lambda5/IGLL1 Antibody

Immunohistochemistry-Paraffin: Lambda5/IGLL1 Antibody [NBP2-56431]

Immunohistochemistry-Paraffin: Lambda5/IGLL1 Antibody [NBP2-56431]

Immunohistochemistry-Paraffin: Lambda5/IGLL1 Antibody [NBP2-56431] - Staining of human cerebral cortex shows low expression as expected.
Immunohistochemistry-Paraffin: Lambda5/IGLL1 Antibody [NBP2-56431]

Immunohistochemistry-Paraffin: Lambda5/IGLL1 Antibody [NBP2-56431]

Immunohistochemistry-Paraffin: Lambda5/IGLL1 Antibody [NBP2-56431] - Staining of human bone marrow shows high expression.
Immunohistochemistry-Paraffin: Lambda5/IGLL1 Antibody [NBP2-56431]

Immunohistochemistry-Paraffin: Lambda5/IGLL1 Antibody [NBP2-56431]

Immunohistochemistry-Paraffin: Lambda5/IGLL1 Antibody [NBP2-56431] - Staining in human bone marrow and cerebral cortex tissues using anti-IGLL1 antibody. Corresponding IGLL1 RNA-seq data are presented for the same tissues.

Applications for Lambda5/IGLL1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lambda5/IGLL1

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Immunoglobulin Lambda-Like Polypeptide 1

Alternate Names

AGM2, CD179b, IGL5, IGLJ14.1, IGLL1, IGO, IGVPB, VPREB2

Gene Symbol

IGLL1

Additional Lambda5/IGLL1 Products

Product Documents for Lambda5/IGLL1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Lambda5/IGLL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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