Laminin S/Laminin beta 2 Antibody (CL2976)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-42386

Novus Biologicals, part of Bio-Techne
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NBP2-42386
NBP2-42386-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL2976

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Laminin S Antibodies »

Product Summary for Laminin S/Laminin beta 2 Antibody (CL2976)

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DLTDVQDENFNANHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPG

Epitope

NANHALSGLERDRLA

Reactivity Notes

Expected to cross react based on sequence identity: Mouse (83%), Rat (82%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Laminin S/Laminin beta 2 Antibody (CL2976)

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Analysis in human lung tissue.
Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Staining of human lymph node shows absence of immunoreactivity in lymphoid cells (negative control).
Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2976) [NBP2-42386] - Analysis of purified human recombinant Laminin-421, Laminin-521, Laminin-332 and Laminin-111.
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Applications for Laminin S/Laminin beta 2 Antibody (CL2976)

Application
Recommended Usage

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Paraffin

1:5000-1:1000

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Laminin S

The Laminins comprise a growing family of disulfide-linked heterotrimers consisting of three genetically distinct polypeptide chains, designated alpha, beta and gamma. A major component of the basal lamina, Laminins play a crucial role in providing a scaffolding upon which tissues are assembled and which serves as a physical barrier separating specialized tissues. During embryogenesis and early development, cells migrate along basement membranes, which are required for the polarization of cells. The beta-2 laminin chain plays a role in melanoma spread, promoting tumor migration along the abluminal surface of vessel, a phenomenon which has been termed extra-vascular migratory metastasis.

Long Name

Laminin, beta 2

Alternate Names

LAMB2, Laminin beta 2

Gene Symbol

LAMB2

UniProt

P55268 (Human)

Additional Laminin S Products

Product Documents for Laminin S/Laminin beta 2 Antibody (CL2976)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Laminin S/Laminin beta 2 Antibody (CL2976)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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