Langerin/CD207 Antibody (918A11)

Novus Biologicals, part of Bio-Techne | Catalog # DDX0376P-100

Novus Biologicals, part of Bio-Techne
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DDX0376P-100
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG1 Clone # 918A11

Concentration

0.5 mg/ml

View all Langerin/CD207 Antibodies »

Product Specifications

Immunogen

Langerin/CD207 was used as immunogen.

Reactivity Notes

Human, Mouse, Rat

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Scientific Data Images for Langerin/CD207 Antibody (918A11)

Immunocytochemistry/ Immunofluorescence: Langerin/CD207 Antibody (918A11) [DDX0376P-100]

Immunocytochemistry/ Immunofluorescence: Langerin/CD207 Antibody (918A11) [DDX0376P-100]

Immunocytochemistry/Immunofluorescence: Langerin/CD207 Antibody (918A11) [DDX0376P-100] - Staining of mouse epidermal sheet.
Flow Cytometry: Langerin/CD207 Antibody (918A11) [DDX0376P-100]

Flow Cytometry: Langerin/CD207 Antibody (918A11) [DDX0376P-100]

Flow Cytometry: Langerin/CD207 Antibody (918A11) [DDX0376P-100] - Surface FACS staining of Langerin transfected COP5 cells.
Immunocytochemistry/ Immunofluorescence: Langerin/CD207 Antibody (918A11) [DDX0376P-100]

Immunocytochemistry/ Immunofluorescence: Langerin/CD207 Antibody (918A11) [DDX0376P-100]

Immunocytochemistry/Immunofluorescence: Langerin/CD207 Antibody (918A11) [DDX0376P-100] - Staining of mock (left) and Langerin (right) transfected COP5 cells.

Applications for Langerin/CD207 Antibody (918A11)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500
Application Notes
Permeabilization is recommended for flow cytometry.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl (pH 8.0)

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Langerin/CD207

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Alternate Names

CD207, DDX0376-TDS

Gene Symbol

CD207

Additional Langerin/CD207 Products

Product Documents for Langerin/CD207 Antibody (918A11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Langerin/CD207 Antibody (918A11)

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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