Langerin/CD207 Antibody (923B7)

Novus Biologicals, part of Bio-Techne | Catalog # DDX0373P-100

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat, Porcine

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 923B7

Concentration

0.5 mg/ml

View all Langerin/CD207 Antibodies »

Product Specifications

Immunogen

Langerin/CD207 was used as immunogen.

Reactivity Notes

Human, Mouse, Rat, Porcine

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Scientific Data Images for Langerin/CD207 Antibody (923B7)

Immunohistochemistry-Frozen: Langerin/CD207 Antibody (923B7) [DDX0373P-100]

Immunohistochemistry-Frozen: Langerin/CD207 Antibody (923B7) [DDX0373P-100]

Immunohistochemistry-Frozen: Langerin/CD207 Antibody (923B7) [DDX0373P-100] - Langerin (red) stained human skin section at 20x magnification. Section counterstained with DAPI. Sections were fixed with 4% PFA PBS, permeabilized with 0.5% Triton TBS Ca/Azide, and blocked with 5% BSA TBS Ca/Azide prior to staining with anti-Langerin antibody diluted 1:100 at 37C for 1 hour. A secondary antibody was applied, and sections were counterstained with DAPI. Image from a verified customer review.
Immunohistochemistry: Langerin/CD207 Antibody (923B7) [DDX0373P-100]

Immunohistochemistry: Langerin/CD207 Antibody (923B7) [DDX0373P-100]

Immunohistochemistry: Langerin/CD207 Antibody (923B7) [DDX0373P-100] - IHC on human skin cryosectionswith 923B7-HRP

Applications for Langerin/CD207 Antibody (923B7)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Reviewed Applications

Read 1 review rated 5 using DDX0373P-100 in the following applications:

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl (pH 8.0)

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Langerin/CD207

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Alternate Names

CD207

Gene Symbol

CD207

Additional Langerin/CD207 Products

Product Documents for Langerin/CD207 Antibody (923B7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Langerin/CD207 Antibody (923B7)

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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