Langerin/CD207 Antibody (DCGM4/122D5)

Novus Biologicals, part of Bio-Techne | Catalog # DDX0363P-100

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Canine

Cited:

Human

Applications

Validated:

Binding Activity, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Cited:

Flow Cytometry, IF/IHC, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # DCGM4/122D5

Concentration

0.5 mg/ml

View all Langerin/CD207 Antibodies »

Product Specifications

Immunogen

Langerin/CD207 was used as immunogen.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Langerin/CD207 Antibody (DCGM4/122D5)

Western Blot: Langerin/CD207 Antibody (DCGM4/122D5) [DDX0363P-100]

Western Blot: Langerin/CD207 Antibody (DCGM4/122D5) [DDX0363P-100]

Western Blot: Langerin/CD207 Antibody (DCGM4/122D5) [DDX0363P-100] - Western-blot DCGM4 1: non-reduced 2: reduced
Immunohistochemistry: Langerin/CD207 Antibody (DCGM4/122D5) [DDX0363P-100]

Immunohistochemistry: Langerin/CD207 Antibody (DCGM4/122D5) [DDX0363P-100]

Immunohistochemistry: Langerin/CD207 Antibody (DCGM4/122D5) [DDX0363P-100] - lung tumor tissue section
Flow Cytometry: Langerin/CD207 Antibody (DCGM4/122D5) [DDX0363P-100]
View 9 more images

Applications for Langerin/CD207 Antibody (DCGM4/122D5)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Western Blot

1:100-1:2000
Application Notes
Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID: 30223113).

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl (pH 8.0)

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Langerin/CD207

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Alternate Names

CD207

Gene Symbol

CD207

Additional Langerin/CD207 Products

Product Documents for Langerin/CD207 Antibody (DCGM4/122D5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Langerin/CD207 Antibody (DCGM4/122D5)

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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