LAPTM4B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59416

Novus Biologicals, part of Bio-Techne
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NBP1-59416
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all LAPTM4B Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to LAPTM4B(lysosomal associated protein transmembrane 4 beta) The peptide sequence was selected from the middle region of LAPTM4B. Peptide sequence YPNSIQEYIRQLPPNFPYRDDVMSVNPTCLVLIILLFISIILTFKGYLIS. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for LAPTM4B Antibody

Western Blot: LAPTM4B Antibody [NBP1-59416]

Western Blot: LAPTM4B Antibody [NBP1-59416]

Western Blot: LAPTM4B Antibody [NBP1-59416] - Titration: 0.2-1 ug/ml, Positive Control: 293T cell lysate.
Immunohistochemistry-Paraffin: LAPTM4B Antibody [NBP1-59416]

Immunohistochemistry-Paraffin: LAPTM4B Antibody [NBP1-59416]

Immunohistochemistry-Paraffin: LAPTM4B Antibody [NBP1-59416] - Paraffin Embedded Tissue: Human Pineal Tissue Observed Staining: Membrane and cytoplasmic in processes of pinealocytes and intersticial cells

Applications for LAPTM4B Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LAPTM4B

LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.

Alternate Names

LAPTM4beta, LC27, lysosomal associated protein transmembrane 4 beta, lysosomal protein transmembrane 4 beta, lysosomal-associated transmembrane protein 4B, Lysosome-associated transmembrane protein 4-beta

Entrez Gene IDs

55353 (Human)

Gene Symbol

LAPTM4B

UniProt

Q86VI4-3 (Human)

Additional LAPTM4B Products

Product Documents for LAPTM4B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LAPTM4B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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