Latent TGF-beta bp1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-79806

Novus Biologicals, part of Bio-Techne
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NBP1-79806
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Latent TGF-beta bp1 Antibodies »

Product Specifications

Immunogen

Synthetic peptide directed towards the C terminal of human LTBP1The immunogen for this antibody is LTBP1. Peptide sequence NVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

154 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Latent TGF-beta bp1 Antibody

Western Blot: Latent TGF-beta bp1 Antibody [NBP1-79806]

Western Blot: Latent TGF-beta bp1 Antibody [NBP1-79806]

Western Blot: LTBP1 Antibody [NBP1-79806] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

Applications for Latent TGF-beta bp1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Latent TGF-beta bp1

LTBP1, also known as latent-transforming growth factor beta-binding protein 1, consists of five isoforms of sizes 186.8 kDa, 152.9 kDa, 147.2 kDa, 186.9 kDa, and 153 kDa and is involved in directing and regulating the activity of TGFB1. Current research is being conducted on diseases and disorders such as cataracts, fibrosis, geleophysic dysplasia, macular degeneration, aortic aneurysm, malignant glioma, hepatitis, vaginitis, scleroderma, and nephropathy. The protein is involved in extracellular matrix organization, mitochondrial apoptosis, TGF-beta signaling, and GSK3 signaling pathways, where it interacts with FN1, FBN2, TGFB1, ITGB5, and ATN1.

Alternate Names

Latent TGFbeta bp1, LTBP1

Gene Symbol

LTBP1

UniProt

NP_000618 (Human)

Additional Latent TGF-beta bp1 Products

Product Documents for Latent TGF-beta bp1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Latent TGF-beta bp1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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