LIM Kinase 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-97870

Novus Biologicals, part of Bio-Techne
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NBP2-97870-100ul
NBP2-97870-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all LIM Kinase 1 Antibodies »

Product Summary for LIM Kinase 1 Antibody

Immunogen

Produced in rabbits immunized with E. coli-derived Human LIM Kinase 1 fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for LIM Kinase 1 Antibody

Immunohistochemistry-Paraffin: LIM Kinase 1 Antibody [NBP2-97870]

Immunohistochemistry-Paraffin: LIM Kinase 1 Antibody [NBP2-97870]

Immunohistochemistry-Paraffin: LIM Kinase 1 Antibody [NBP2-97870] - Immunochemical staining of human LIM Kinase 1 in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
LIM Kinase 1 Antibody

Immunohistochemistry-Paraffin: LIM Kinase 1 Antibody [NBP2-97870] -

Immunohistochemistry-Paraffin: LIM Kinase 1 Antibody [NBP2-97870] - Staining of human LIMK1 in human brain with rabbit polyclonal antibody at 1:100 dilution.

Applications for LIM Kinase 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunohistochemistry-Paraffin

1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LIM Kinase 1

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.

Long Name

LIM domain kinase 1

Alternate Names

LIMK, LIMK-1, LIMK1

Gene Symbol

LIMK1

Additional LIM Kinase 1 Products

Product Documents for LIM Kinase 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LIM Kinase 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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