LIN-28A Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77383

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all LIN-28A Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human Lin28. The immunogen is located within the last 50 amino acids of Lin28. Amino Acid Squence: GPSAQGKPTYFREEE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%)

Marker

Undifferentiated human embryonic stem cell Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LIN-28A Antibody - BSA Free

Western Blot: LIN-28A AntibodyBSA Free [NBP1-77383]

Western Blot: LIN-28A AntibodyBSA Free [NBP1-77383]

Western Blot: LIN-28A Antibody [NBP1-77383] - Analysis of LIN28 in Raji cell lysate with LIN28 antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: LIN-28A Antibody - BSA Free [NBP1-77383]

Immunocytochemistry/ Immunofluorescence: LIN-28A Antibody - BSA Free [NBP1-77383]

Immunocytochemistry/Immunofluorescence: LIN-28A Antibody [NBP1-77383] - LIN28 in human spleen tissue with LIN28 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: LIN-28A Antibody - BSA Free [NBP1-77383]

Immunohistochemistry-Paraffin: LIN-28A Antibody - BSA Free [NBP1-77383]

Immunohistochemistry-Paraffin: LIN-28A Antibody [NBP1-77383] - LIN-28A in human spleen tissue with LIN-28A antibody at 5 ug/mL.

Applications for LIN-28A Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: LIN-28A

Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.

Long Name

RNA-binding Protein LIN-28

Alternate Names

CSDD1, LIN28, LIN28A, Tex17, ZCCHC1

Gene Symbol

LIN28A

UniProt

EAX07814 (Human)

Additional LIN-28A Products

Product Documents for LIN-28A Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LIN-28A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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