LLGL2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81753

Novus Biologicals, part of Bio-Techne
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NBP1-81753
NBP1-81753-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LLGL2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRARNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLSNGGAE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LLGL2 Antibody

Immunocytochemistry/ Immunofluorescence: LLGL2 Antibody [NBP1-81753]

Immunocytochemistry/ Immunofluorescence: LLGL2 Antibody [NBP1-81753]

Immunocytochemistry/Immunofluorescence: LLGL2 Antibody [NBP1-81753] - Staining of human cell line U-2 OS shows localization to cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: LLGL2 Antibody [NBP1-81753]

Immunohistochemistry-Paraffin: LLGL2 Antibody [NBP1-81753]

Immunohistochemistry-Paraffin: LLGL2 Antibody [NBP1-81753] - Staining of human small intestine shows moderate to strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: LLGL2 Antibody [NBP1-81753]

Immunohistochemistry-Paraffin: LLGL2 Antibody [NBP1-81753]

Immunohistochemistry-Paraffin: LLGL2 Antibody [NBP1-81753] - Staining of human fallopian tube shows moderate to strong cytoplasmic postivity in glandular cells.
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Applications for LLGL2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LLGL2

The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternate Names

HGLlethal giant larvae (Drosophila) homolog 2, human giant larvae homolog, lethal giant larvae homolog 2 (Drosophila), lethal(2) giant larvae protein homolog 2, LGL2

Gene Symbol

LLGL2

Additional LLGL2 Products

Product Documents for LLGL2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LLGL2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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