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LMAN1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19366

Novus Biologicals, part of Bio-Techne
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NBP2-19366

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human LMAN1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (81%).

Localization

Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein; Golgi apparatus membrane; Single-pass membrane protein; Endoplasmic reticulum membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for LMAN1 Antibody

Western Blot: LMAN1 Antibody [NBP2-19366]

Western Blot: LMAN1 Antibody [NBP2-19366]

Western Blot: LMAN1 Antibody [NBP2-19366] - Sample (30 ug of whole cell lysate) A: Hela 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: LMAN1 Antibody [NBP2-19366]

Immunohistochemistry-Paraffin: LMAN1 Antibody [NBP2-19366]

Immunohistochemistry-Paraffin: LMAN1 Antibody [NBP2-19366] - LMAN1 antibody [N1C1] detects LMAN1 protein at cytosol on gastric carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded gastric carcinoma. LMAN1 antibody [N1C1] dilution: 1:500.
Immunohistochemistry-Paraffin: LMAN1 Antibody [NBP2-19366]

Immunohistochemistry-Paraffin: LMAN1 Antibody [NBP2-19366]

Immunohistochemistry-Paraffin: LMAN1 Antibody [NBP2-19366] - Immunohistochemical analysis of paraffin-embedded Breast ca, using antibody at 1:500 dilution.

Applications for LMAN1 Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: LMAN1

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]

Alternate Names

ERGIC-53, ERGIC53ER-Golgi intermediate compartment 53 kDa protein, F5F8Dendoplasmic reticulum-golgi intermediate compartment protein 53, FMFD1, gp58, intracellular mannose specific lectin, Intracellular mannose-specific lectin MR60, Lectin mannose-binding 1, lectin, mannose-binding, 1, MCFD1coagulation factor V-factor VIII combined deficiency, MR60, protein ERGIC-53

Gene Symbol

LMAN1

UniProt

Additional LMAN1 Products

Product Documents for LMAN1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LMAN1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.