LMP7/PSMB8 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NB120-3329
Key Product Details
Species Reactivity
Validated:
Human, Mouse
Cited:
Human, Mouse
Predicted:
Rat (100%), Sheep (100%). Backed by our 100% Guarantee.
Applications
Validated:
Immunocytochemistry/ Immunofluorescence, Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
1 mg/ml
Product Specifications
Immunogen
Synthetic Peptide: C V(259) E S T D V S D L L H Q Y R E A(274)
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for LMP7/PSMB8 Antibody
![Western Blot: LMP7/PSMB8 Antibody [NB120-3329]](https://resources.bio-techne.com/images/products/LMP7-PSMB8-Antibody-Western-Blot-NB120-3329-img0003.jpg "Western Blot: LMP7/PSMB8 Antibody [NB120-3329]")
Western Blot: LMP7/PSMB8 Antibody [NB120-3329]
Western Blot: LMP7/PSMB8 Antibody [NB120-3329] - Analysis of HeLa cell extract.Applications for LMP7/PSMB8 Antibody
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
5 ug/ml
Western Blot
1.0 ug/ml
Formulation, Preparation, and Storage
Purification
Immunogen affinity purified
Formulation
PBS with 1 mg/ml BSA
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: LMP7/PSMB8
The 26S proteasome is an ATP-dependent, multisubunit (~31), barrel-shaped molecular machine with an apparent molecular weight of ~2.5 MDa. It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes. The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit. An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation. Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway. Some examples of affected proteins include those linked to cystic fibrosis, Angelman's syndrome, and Liddle syndrome.
Long Name
Large Multifunctional Protease 7
Alternate Names
ALDD, D6S216E, JMP, NKJO, Proteasome Component C13, Proteasome Subunit Y2, PSMB5i, PSMB8, RING10
Entrez Gene IDs
5696 (Human)
Gene Symbol
PSMB8
UniProt
Additional LMP7/PSMB8 Products
Product Documents for LMP7/PSMB8 Antibody
Product Specific Notices for LMP7/PSMB8 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Loading...
Loading...
Loading...
Loading...