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LMX1b Antibody (1D12)

Novus Biologicals, part of Bio-Techne | Catalog # H00004010-M08

Novus Biologicals, part of Bio-Techne
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H00004010-M08

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1D12

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

LMX1B (NP_002307, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALE

Specificity

LMX1B - LIM homeobox transcription factor 1, beta (1D12)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for LMX1b Antibody (1D12)

Immunohistochemistry-Paraffin: LMX1b Antibody (1D12) [H00004010-M08]

Immunohistochemistry-Paraffin: LMX1b Antibody (1D12) [H00004010-M08]

Immunohistochemistry-Paraffin: LMX1b Antibody (1D12) [H00004010-M08] - Analysis of monoclonal antibody to LMX1B on formalin-fixed paraffin-embedded human testis. Antibody concentration 3 ug/ml
ELISA: LMX1b Antibody (1D12) [H00004010-M08]

ELISA: LMX1b Antibody (1D12) [H00004010-M08]

ELISA: LMX1b Antibody (1D12) [H00004010-M08] - Detection limit for recombinant GST tagged LMX1B is approximately 0.3ng/ml as a capture antibody.

Applications for LMX1b Antibody (1D12)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: LMX1b

LMX1B is a gene that codes for a protein with three isoforms, measuring 402, 395, and 406 amino acids in length with weights of approximately 45, 44, and 45 kDa respectively. LMX1B is necessary for the specification of dorsal limb fate. Current studies are being done on several diseases and disorders related to this gene including Meier-Gorlin syndrome, steroid-resistant nephrotic syndrome, sex reversal, attention deficit hyperactivity disorder, cleft lip/palate, familial Mediterranean fever, genitopatellar syndrome, major depressive disorder, nail dysplasia, short stature, heart block, and neuronitis. LMX1B has also been shown to have interactions with LDB1, TCF3, SSBP3, ALX4, and LDB2 in pathways such as the SIDS susceptibility pathway.

Alternate Names

LIM homeobox transcription factor 1, beta, LIM homeobox transcription factor 1-beta, LIM/homeobox protein 1.2, LIM/homeobox protein LMX1B, LMX1.2, LMX-1.2, MGC138325, MGC142051, NPS1

Entrez Gene IDs

4010 (Human)

Gene Symbol

LMX1B

Additional LMX1b Products

Product Documents for LMX1b Antibody (1D12)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LMX1b Antibody (1D12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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