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Lnx1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58844

Novus Biologicals, part of Bio-Techne
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NBP2-58844
NBP2-58844-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: RSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFPRLYHLIPDGEITSIKINRV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Lnx1 Antibody

Immunocytochemistry/ Immunofluorescence: Lnx1 Antibody [NBP2-58844]

Immunocytochemistry/ Immunofluorescence: Lnx1 Antibody [NBP2-58844]

Immunocytochemistry/Immunofluorescence: Lnx1 Antibody [NBP2-58844] - Staining of human cell line MCF7 shows localization to cell junctions.

Applications for Lnx1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lnx1

Lnx1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq]

Alternate Names

EC 6.3.2.-, ligand of numb-protein X 1ligand of numb-protein X, LNXmulti-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX, MPDZ, Numb-binding protein 1, PDZ domain-containing ring finger protein 2, PDZRN2E3 ubiquitin-protein ligase LNX

Gene Symbol

LNX1

Additional Lnx1 Products

Product Documents for Lnx1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Lnx1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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