LPAR1/LPA1/EDG-2 Antibody (3U1Q0)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15851

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 3U1Q0

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all LPAR1/LPA1/EDG-2 Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LPAR1/LPA1/EDG-2 (Q92633). MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGL

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LPAR1/LPA1/EDG-2 Antibody (3U1Q0)

Western Blot: LPAR1/LPA1/EDG-2 Antibody (3U1Q0) [NBP3-15851]

Western Blot: LPAR1/LPA1/EDG-2 Antibody (3U1Q0) [NBP3-15851]

Western Blot: LPAR1/LPA1/EDG-2 Antibody (3U1Q0) [NBP3-15851] - Analysis of extracts of various cell lines, using LPAR1/LPA1/EDG-2 Rabbit mAb (NBP3-15851) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Applications for LPAR1/LPA1/EDG-2 Antibody (3U1Q0)

Application
Recommended Usage

Western Blot

1:500 -1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: LPAR1/LPA1/EDG-2

EDG2 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several proteins not used within 12 hours. Edg2 has been reported in most human tissues, and is especially abundant in brain cortical regions. ESTs have been isolated from bone, brain, breast, connective tissue, embryo, heart/melanocyte/uterus, lung, prostate and uterus libraries.

Long Name

Lysophosphatidic Acid Receptor 1

Alternate Names

EDG2, GPCR26, GPR26, LPA1, rec.1.3, vzg-1

Gene Symbol

LPAR1

Additional LPAR1/LPA1/EDG-2 Products

Product Documents for LPAR1/LPA1/EDG-2 Antibody (3U1Q0)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LPAR1/LPA1/EDG-2 Antibody (3U1Q0)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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