LPAR1/LPA1/EDG-2 Antibody (SR1651)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21799

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21799-100ul
NBP3-21799-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1651

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all LPAR1/LPA1/EDG-2 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human LPAR1/LPA1/EDG-2 (Uniprot #: Q92633)

Specificity

Detects endogenous levels of total LPAR1/LPA1/EDG-2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for LPAR1/LPA1/EDG-2 Antibody (SR1651)

Western Blot: LPAR1/LPA1/EDG-2 Antibody (SR1651) [NBP3-21799] -

Western Blot: LPAR1/LPA1/EDG-2 Antibody (SR1651) [NBP3-21799] - Western blot analysis using NBP3-21799 in A375 cell lysate.

Applications for LPAR1/LPA1/EDG-2 Antibody (SR1651)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LPAR1/LPA1/EDG-2

EDG2 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several proteins not used within 12 hours. Edg2 has been reported in most human tissues, and is especially abundant in brain cortical regions. ESTs have been isolated from bone, brain, breast, connective tissue, embryo, heart/melanocyte/uterus, lung, prostate and uterus libraries.

Long Name

Lysophosphatidic Acid Receptor 1

Alternate Names

EDG2, GPCR26, GPR26, LPA1, rec.1.3, vzg-1

Gene Symbol

LPAR1

Additional LPAR1/LPA1/EDG-2 Products

Product Documents for LPAR1/LPA1/EDG-2 Antibody (SR1651)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LPAR1/LPA1/EDG-2 Antibody (SR1651)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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