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LPAR1/LPA1/EDG-2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS212

Novus Biologicals, part of Bio-Techne
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NLS212

Key Product Details

Species Reactivity

Validated:

Human, Rat, Monkey, Primate

Cited:

Human, Rat

Predicted:

Avian (93%), Bat (93%), Bovine (93%), Canine (93%), Chicken (93%), Equine (93%), Hamster (93%), Mouse (93%), Opossum (93%), Porcine (93%), Rabbit (93%), Sheep (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 15 amino acid peptide from N-terminal extracellular domain of human LPAR1/LPA1/EDG-2.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Xenopus (87%), Zebrafish (87%). Rat reactivity reported in (PMID: 23451264).

Localization

Cell Membrane

Specificity

Human EDG2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DDX60 (53%), ACER3 (47%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for LPAR1/LPA1/EDG-2 Antibody - BSA Free

Immunohistochemistry-Paraffin: LPAR1/LPA1/EDG-2 Antibody - BSA Free [NLS212]

Immunohistochemistry-Paraffin: LPAR1/LPA1/EDG-2 Antibody - BSA Free [NLS212]

Immunohistochemistry-Paraffin: LPAR1/LPA1/EDG-2 Antibody [NLS212] - Skin, Melanoma
Immunohistochemistry-Paraffin: LPAR1/LPA1/EDG-2 Antibody - BSA Free [NLS212]

Immunohistochemistry-Paraffin: LPAR1/LPA1/EDG-2 Antibody - BSA Free [NLS212]

Immunohistochemistry-Paraffin: LPAR1/LPA1/EDG-2 Antibody [NLS212] - Brain, Glioblastoma

Applications for LPAR1/LPA1/EDG-2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1 - 2 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID: 31546971)..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: LPAR1/LPA1/EDG-2

Edg2, a Lysophospholipid/Lysosphingolipid Receptor, mediates growth factor-like activities such as proliferation, platelet aggregation, and chemotaxis. Edg2 is involved in myelin formation or maintenance. It is activated by platelet-derived lysophosphatidic acid (LPA), a lipid metabolite present in serum that acts ubiquitously. Although alternate translation start codons and polyadenylation sites have been reported, the alternative splicing transcripts each encode identical proteins. Edg2 has been reported in most human tissues, and is especially abundant in brain cortical regions. ESTs have been isolated from bone, brain, breast, connective tissue, embryo, heart/melanocyte/uterus, lung, prostate, and uterus libraries.

Long Name

Lysophosphatidic Acid Receptor 1

Alternate Names

EDG2, GPCR26, GPR26, LPA1, rec.1.3, vzg-1

Entrez Gene IDs

1902 (Human)

Gene Symbol

LPAR1

UniProt

Additional LPAR1/LPA1/EDG-2 Products

Product Documents for LPAR1/LPA1/EDG-2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LPAR1/LPA1/EDG-2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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