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LPAR2/LPA2/EDG-4 Antibody - C-terminus

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-30841

Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-30841-100ug
NBP3-30841-25ug

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Antibody raised against a unique synthetic peptide derived from the N-terminal of the human LPAR2/LPA2/EDG-4 protein. Antigen sequence differs in mouse and rat by one amino acid.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LPAR2/LPA2/EDG-4 Antibody - C-terminus

LPAR2/LPA2/EDG-4 Antibody - C-terminus

Western Blot: LPAR2/LPA2/EDG-4 Antibody - C-terminus [NBP3-30841] -

Western Blot: LPAR2/LPA2/EDG-4 Antibody - C-terminus [NBP3-30841] - Western blot analysis using EDG4/LPA2 (NT)antibody at 5 ug/ml onRH7777 cells transfected with EDG4/LPA2 protein in the absence (1) and presence (2) of blocking peptide.

Applications for LPAR2/LPA2/EDG-4 Antibody - C-terminus

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Western blot should be visualized using a high sensitivity secondary/substrate system (i.e. Pierce's SuperSignal West Femto Maximum Sensitivity Substrate)..

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

Phosphate buffered saline

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: LPAR2/LPA2/EDG-4

Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.

Long Name

Lysophosphatidic Acid Receptor 2

Alternate Names

EDG4, LPA2, LPAR2

Gene Symbol

LPAR2

Additional LPAR2/LPA2/EDG-4 Products

Product Documents for LPAR2/LPA2/EDG-4 Antibody - C-terminus

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LPAR2/LPA2/EDG-4 Antibody - C-terminus

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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