LRP-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48497

Novus Biologicals, part of Bio-Techne
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NBP2-48497
NBP2-48497-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LRP-1 Antibodies »

Product Summary for LRP-1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: STCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEGSRCEVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LRP-1 Antibody

Immunocytochemistry/ Immunofluorescence: LRP-1 Antibody [NBP2-48497]

Immunocytochemistry/ Immunofluorescence: LRP-1 Antibody [NBP2-48497]

Immunocytochemistry/Immunofluorescence: LRP-1 Antibody [NBP2-48497] - Staining of human cell line RH-30 shows localization to nucleoplasm & vesicles.
Immunohistochemistry-Paraffin: LRP-1 Antibody [NBP2-48497]

Immunohistochemistry-Paraffin: LRP-1 Antibody [NBP2-48497]

Immunohistochemistry-Paraffin: LRP-1 Antibody [NBP2-48497] - Staining of human placenta shows moderate cytoplasmic and membranous positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: LRP-1 Antibody [NBP2-48497]

Immunohistochemistry-Paraffin: LRP-1 Antibody [NBP2-48497]

Immunohistochemistry-Paraffin: LRP-1 Antibody [NBP2-48497] - Staining of human cerebral cortex shows weak cytoplasmic positivity in neurons.
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Applications for LRP-1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation/Permeabilization: PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LRP-1

LRP-1 (low-density lipoprotein receptor-related protein 1) is a large type I transmembrane protein belonging to the LDL receptor superfamily. The extracellular domain of LRP-1 is organized in four clusters of ligand-binding repeats that recognizes at least 30 different ligands. The amino acid sequence of human and mouse LRP-1 cluster II share 100% identity.

Long Name

LDL Receptor-related Protein 1

Alternate Names

A2MR, Alpha-2-Macroglobulin Receptor, APOER, Apolipoprotein E receptor, APR, CD91, CD91 antigen, EC 1.1.1.94, EC 3.4.21.9, IGFBP3R, low density lipoprotein receptor-related protein 1, LRP, LRP-1, LRP1A, prolow-density lipoprotein receptor-related protein 1, TbetaR-V/LRP-1/IGFBP-3 receptor, TGFBR5, type V tgf-beta receptor

Gene Symbol

LRP1

Additional LRP-1 Products

Product Documents for LRP-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LRP-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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