LRP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-39033

Novus Biologicals, part of Bio-Techne
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NBP2-39033-25ul
NBP2-39033
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Megalin/LRP2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: NNDRIYWSDFKEDVIETIKYDGTDRRVIAKEAMNPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQVRIFHQLRYNKSVP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LRP2 Antibody

Immunohistochemistry-Paraffin: LRP2 Antibody [NBP2-39033]

Immunohistochemistry-Paraffin: LRP2 Antibody [NBP2-39033]

Immunohistochemistry-Paraffin: LRP2 Antibody [NBP2-39033] - Analysis in human parathyroid gland and placenta tissues. Corresponding LRP2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: LRP2 Antibody [NBP2-39033]

Immunohistochemistry-Paraffin: LRP2 Antibody [NBP2-39033]

Immunohistochemistry-Paraffin: LRP2 Antibody [NBP2-39033] - Staining of human placenta shows no positivity in trophoblastic cells as expected.
Immunohistochemistry-Paraffin: LRP2 Antibody [NBP2-39033]

Immunohistochemistry-Paraffin: LRP2 Antibody [NBP2-39033]

Immunohistochemistry-Paraffin: LRP2 Antibody [NBP2-39033] - Staining of human kidney shows strong membranous positivity in cells in tubules.
View 3 more images

Applications for LRP2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:2500 -1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Megalin/LRP2

Megalin/gp330, an approx. 600 kDa transmembrane glycoprotein is a large cell surface receptor that mediates the binding and internalization of a number of structurally and functionally distinct ligands from the lipoprotein and protease inhibitor families.

Long Name

LDL Receptor-related Protein 2

Alternate Names

DBS, gp330, LRP-2, LRP2

Gene Symbol

LRP2

UniProt

P98164

Additional Megalin/LRP2 Products

Product Documents for LRP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LRP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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