LRRC8A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59493

Novus Biologicals, part of Bio-Techne
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NBP1-59493
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all LRRC8A Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to LRRC8A(leucine rich repeat containing 8 family, member A) The peptide sequence was selected from the N terminal of LRRC8A. Peptide sequence IPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDK. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for LRRC8A Antibody

Western Blot: LRRC8A Antibody [NBP1-59493]

Western Blot: LRRC8A Antibody [NBP1-59493]

Western Blot: LRRC8A Antibody [NBP1-59493] - Sample Tissue: Human HepG2 Antibody Dilution: 1.0 ug/ml
Western Blot: LRRC8A Antibody [NBP1-59493]

Western Blot: LRRC8A Antibody [NBP1-59493]

Western Blot: LRRC8A Antibody [NBP1-59493] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

Applications for LRRC8A Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LRRC8A

LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Long Name

Leucine Rich Repeat Containing 8A

Alternate Names

AGM5, KIAA1437, LRRC8, SWELL1

Gene Symbol

LRRC8A

UniProt

Q8IWT6 (Human)

Additional LRRC8A Products

Product Documents for LRRC8A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LRRC8A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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