LSP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-74048

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

IF/IHC, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all LSP1 Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding a C-terminal portion of the human LSP1 protein (between amino acids 250-339) [UniProt P33241].

Localization

Cytoplasmic and membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LSP1 Antibody - BSA Free

Western Blot: LSP1 AntibodyBSA Free [NBP1-74048]

Western Blot: LSP1 AntibodyBSA Free [NBP1-74048]

Western Blot: LSP1 Antibody [NBP1-74048] - Western blot analysis of LSP1 in Ramos (1) and Daudi (2) cell lysates.
Immunohistochemistry-Paraffin: LSP1 Antibody - BSA Free [NBP1-74048]

Immunohistochemistry-Paraffin: LSP1 Antibody - BSA Free [NBP1-74048]

Immunohistochemistry-Paraffin: LSP1 Antibody [NBP1-74048] - IHC analysis of LSP1 in mouse colon tissue. Abundant membrane staining is visible in the epithelial cells.

Applications for LSP1 Antibody - BSA Free

Application
Recommended Usage

ELISA

0.01-0.1 ug/ml

Immunohistochemistry

1:200

Immunohistochemistry-Paraffin

1:200

Immunoprecipitation

2-5 ug/ml

Western Blot

1.0 - 2.0 ug/ml

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LSP1

Lymphocyte-specific protein 1 (LSP1), also known as 47 kDa actin-binding protein, 52 kDa phosphoprotein, and Lymphocyte-specific antigen WP34, is an intracellular F-actin binding protein. LSP1 is expressed in lymphocytes, neutrophils, macrophages, and endothelium. LSP1 is also found in activated T-lymphocytes. LSP1 is known to function in neutrophil motility regulation, adhesion to fibrinogen matrix proteins, and trans-endothelial migration. LSP1 is phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. The phosphorylation by protein kinase C induces translocation of LSP1 from the cell membrane to the cytoplasm. Phosphorylation of LSP1 by MAPKAPK2 regulates neutrophil chemotaxis.

Alternate Names

47 kDa actin binding protein, 47 kDa actin-binding protein, 52 kDa phosphoprotein, F-actin binding and cytoskeleton associated protein, leufactin (leukocyte F-actin binding protein), leukocyte-specific protein 1, lymphocyte-specific protein 1, lymphocyte-specific protein pp52, pp52, WP34Lymphocyte-specific antigen WP34

Entrez Gene IDs

4046 (Human); 16985 (Mouse)

Gene Symbol

LSP1

UniProt

P33241 (Human)

Additional LSP1 Products

Product Documents for LSP1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LSP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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