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LSP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86852

Novus Biologicals, part of Bio-Techne
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NBP1-86852
NBP1-86852-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PRTPSPLVLEGTIEQSSPPLSPTTKLIDRTESLNRSIEKSNSVKKSQPDLPISKIDQWLEQYTQAIETAGRTPKLARQASIELPSMAVASTK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%), Rat (82%). Human reactivity reported in scientific literature (PMID: 25674539).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LSP1 Antibody

Western Blot: LSP1 Antibody [NBP1-86852]

Western Blot: LSP1 Antibody [NBP1-86852]

Western Blot: LSP1 Antibody [NBP1-86852] - Analysis in human cell line HDLM-2.
Immunohistochemistry-Paraffin: LSP1 Antibody [NBP1-86852]

Immunohistochemistry-Paraffin: LSP1 Antibody [NBP1-86852]

Immunohistochemistry-Paraffin: LSP1 Antibody [NBP1-86852] - Staining in human spleen and cerebral cortex tissues using anti-LSP1 antibody. Corresponding LSP1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: LSP1 Antibody [NBP1-86852]

Immunohistochemistry-Paraffin: LSP1 Antibody [NBP1-86852]

Immunohistochemistry-Paraffin: LSP1 Antibody [NBP1-86852] - Staining of human cerebral cortex shows low expression as expected.

Applications for LSP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
IHC reported in scientific literature (PMID: 25674539). For IHC-Paraffin, HIER pH 6 retrieval is recommended. For

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LSP1

LSP1 encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternate Names

47 kDa actin binding protein, 47 kDa actin-binding protein, 52 kDa phosphoprotein, F-actin binding and cytoskeleton associated protein, leufactin (leukocyte F-actin binding protein), leukocyte-specific protein 1, lymphocyte-specific protein 1, lymphocyte-specific protein pp52, pp52, WP34Lymphocyte-specific antigen WP34

Gene Symbol

LSP1

Additional LSP1 Products

Product Documents for LSP1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for LSP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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