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Lumican Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87726

Novus Biologicals, part of Bio-Techne
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NBP1-87726
NBP1-87726-25ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTF

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 31582785). Rat (89%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Lumican Antibody

Western Blot: Lumican Antibody [NBP1-87726]

Western Blot: Lumican Antibody [NBP1-87726]

Western Blot: Lumican Antibody [NBP1-87726] - Validation of extracellular matrix proteins differentially expressed in CNV patients. Representative Western blot images cropped from different gels with different exposure. Statistical analysis performed by unpaired t-test (**p < 0.01, ***p < 0.001). Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/s41598-019-50718-8), licensed under a CC-BY license.
Immunohistochemistry-Paraffin: Lumican Antibody [NBP1-87726]

Immunohistochemistry-Paraffin: Lumican Antibody [NBP1-87726]

Immunohistochemistry-Paraffin: Lumican Antibody [NBP1-87726] - Staining of human breast shows moderate to strong cytoplasmic positivity.
Immunohistochemistry-Paraffin: Lumican Antibody [NBP1-87726]

Immunohistochemistry-Paraffin: Lumican Antibody [NBP1-87726]

Immunohistochemistry-Paraffin: Lumican Antibody [NBP1-87726] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.

Applications for Lumican Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

Reported in scientific literature (PMID 25961303)
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lumican

Lumican encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq]

Alternate Names

LDC, LUM, SLRR2D

Gene Symbol

LUM

Additional Lumican Products

Product Documents for Lumican Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Lumican Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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