Lunatic Fringe Antibody (SR1725)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22641

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22641-100ul
NBP3-22641-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1725

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Lunatic Fringe/LFNG Antibodies »

Product Summary for Lunatic Fringe Antibody (SR1725)

Immunogen

A synthesized peptide derived from human Lunatic Fringe (Uniprot #: Q8NES3)

Specificity

Detects endogenous levels of total Lunatic Fringe

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Lunatic Fringe Antibody (SR1725)

Western Blot: Lunatic Fringe Antibody (SR1725) [NBP3-22641] -

Western Blot: Lunatic Fringe Antibody (SR1725) [NBP3-22641] - Western blot analysis using NBP3-22641 in HeLa cell lysate.

Applications for Lunatic Fringe Antibody (SR1725)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lunatic Fringe/LFNG

Lunatic Fringe encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.

Long Name

LFNG O-Fucosylpeptide 3-Beta-N-Acetylglucosaminyltransferase

Alternate Names

EC 2.4.1.222, LFNG, SCDO3

Gene Symbol

LFNG

Additional Lunatic Fringe/LFNG Products

Product Documents for Lunatic Fringe Antibody (SR1725)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Lunatic Fringe Antibody (SR1725)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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