Lunatic Fringe Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59432

Novus Biologicals, part of Bio-Techne
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NBP1-59432
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Lunatic Fringe/LFNG Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to LFNG(LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) The peptide sequence was selected from the N terminal of LFNG. Peptide sequence LSEYFSLLTRARRDAGPPPGAAPRPADGHPRPLAEPLAPRDVFIAVKTTK. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Lunatic Fringe Antibody

Western Blot: Lunatic Fringe Antibody [NBP1-59432]

Western Blot: Lunatic Fringe Antibody [NBP1-59432]

Western Blot: Lunatic Fringe Antibody [NBP1-59432] - Human Muscle lysate, concentration 0.2-1 ug/ml.

Applications for Lunatic Fringe Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lunatic Fringe/LFNG

LFNG is a member of the glycosyltransferase superfamily. It is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in the gene that encodes this protein have been associated with autosomal recessive spondylocostal dysostosis 3. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.

Long Name

LFNG O-Fucosylpeptide 3-Beta-N-Acetylglucosaminyltransferase

Alternate Names

EC 2.4.1.222, LFNG, SCDO3

Entrez Gene IDs

3955 (Human)

Gene Symbol

LFNG

UniProt

Q8NES3-3 (Human)

Additional Lunatic Fringe/LFNG Products

Product Documents for Lunatic Fringe Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lunatic Fringe Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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