LXR beta/NR1H2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76256

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all LXR beta/NR1H2 Antibodies »

Product Summary for LXR beta/NR1H2 Antibody - BSA Free

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus human LXR-B. The immunogen is located within the first 50 amino acids of LXR-B. Amino Acid Squence: SPTVKEEGPEPWPG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LXR beta/NR1H2 Antibody - BSA Free

Western Blot: LXR beta/NR1H2 AntibodyBSA Free [NBP1-76256]

Western Blot: LXR beta/NR1H2 AntibodyBSA Free [NBP1-76256]

Western Blot: LXR beta/NR1H2 Antibody [NBP1-76256] - Human lung tissue lysate with LXR-B antibody at (A) 1 and (B) 2 ug/mL.

Applications for LXR beta/NR1H2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LXR beta/NR1H2

LXR-B belongs to the Liver X Receptor family that encodes highly homologous transcription factors. Like the highly homologous LXR-A, LXR-B forms heterodimers with the retinoic acid receptor RXRalpha, which function as sensors for cellular oxysterols which when activated, increase the expression of genes that control sterol and fatty acid metabolism and homeostasis. Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses. Other studies suggest that genetic variability at the LXR-B gene locus may be a risk factor for Alzheimer's disease. One hypothesis postulates that LXR may be upstream of ApoE and potentiates the risk associated effects of the epsilon3 allele.

Long Name

Liver X Receptor beta

Alternate Names

NER-I, NR1H2, RIP15, UNR

Entrez Gene IDs

7376 (Human)

Gene Symbol

NR1H2

UniProt

P55055 (Human)

Additional LXR beta/NR1H2 Products

Product Documents for LXR beta/NR1H2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LXR beta/NR1H2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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