Lymphotoxin-alpha/TNF-beta Antibody (074)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89370

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-89370-100ul
NBP2-89370-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Sandwich ELISA Detection

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 074

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Lymphotoxin-alpha/TNF-beta Antibodies »

Product Summary for Lymphotoxin-alpha/TNF-beta Antibody (074)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human Lymphotoxin-alpha/TNF-beta (Uniprot#: P01374; Leu35-Leu205).

Specificity

No cross-reactivity in ELISA with: Human TNFaMouse TNFaHuman TNFRII

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Applications for Lymphotoxin-alpha/TNF-beta Antibody (074)

Application
Recommended Usage

Sandwich ELISA Detection

1:1000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Lymphotoxin-alpha/TNF-beta

TNF-beta (tumor necrosis factor beta, lymphotoxin alpha, TNFSF1, TNF ligand superfamily member 1) a member of the TNF ligand superfamily and a potent lymphoid factor, is mainly produced by activated T and B lymphocytes and leukocytes. TNF-beta is also produced by fibroblasts, astrocytes, myeloma cells, endothelial cells and epithelial cells. TNF-beta mediates inflammatory and immune responses, has cytotoxic activity on tumor cells and other target cells and shares many of the same bioactivities as TNF alpha, including regulation of cell proliferation, differentiation and apoptosis. TNF-beta is not species-specific and human TNF-beta is active on murine cells with a slightly reduced specific activity.

Long Name

Tumor Necrosis Factor beta

Alternate Names

LTA, Lymphotoxin alpha, Lymphotoxinalpha, TNF-beta, tnfb, TNFSF1, TNFSF1B

Gene Symbol

LTA

Additional Lymphotoxin-alpha/TNF-beta Products

Product Documents for Lymphotoxin-alpha/TNF-beta Antibody (074)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Lymphotoxin-alpha/TNF-beta Antibody (074)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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