Lysine Hydroxylase 2/PLOD2 Antibody (OTI6D1) [DyLight 350]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-72556UV

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

DyLight 350 (Excitation = 353 nm, Emission = 432 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI6D1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Lysine Hydroxylase 2/PLOD2 Antibodies »

Product Summary for Lysine Hydroxylase 2/PLOD2 Antibody (OTI6D1) [DyLight 350]

Immunogen

Recombinant protein fragment corresponding to amino acids 359-640 of human Lysine Hydroxylase 2/PLOD2 (NP_891988) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Lysine Hydroxylase 2/PLOD2 Antibody (OTI6D1) [DyLight 350]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Lysine Hydroxylase 2/PLOD2

PLOD2 is encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Alternate Names

LH2, PLOD2, TLH

Gene Symbol

PLOD2

Additional Lysine Hydroxylase 2/PLOD2 Products

Product Documents for Lysine Hydroxylase 2/PLOD2 Antibody (OTI6D1) [DyLight 350]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Lysine Hydroxylase 2/PLOD2 Antibody (OTI6D1) [DyLight 350]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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