LZTS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83908

Novus Biologicals, part of Bio-Techne
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NBP1-83908
NBP1-83908-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LZTS1 Antibodies »

Product Summary for LZTS1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TEVNAKASEILGLKAQLKDTRGKLEGLELRTQDLEGALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELQELRAQAALARDMGPPTFPEDVPALQRELERLRAELREERQGHDQMSSGFQHERLVWKE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (86%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LZTS1 Antibody

Western Blot: LZTS1 Antibody [NBP1-83908]

Western Blot: LZTS1 Antibody [NBP1-83908]

Western Blot: LZTS1 Antibody [NBP1-83908] - Analysis in control (vector only transfected HEK293T lysate) and LZTS1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: LZTS1 Antibody [NBP1-83908]

Immunocytochemistry/ Immunofluorescence: LZTS1 Antibody [NBP1-83908]

Immunocytochemistry/Immunofluorescence: LZTS1 Antibody [NBP1-83908] - Immunofluorescent staining of human cell line SK-MEL-30 shows localization to plasma membrane.
Immunohistochemistry-Paraffin: LZTS1 Antibody [NBP1-83908]

Immunohistochemistry-Paraffin: LZTS1 Antibody [NBP1-83908]

Immunohistochemistry-Paraffin: LZTS1 Antibody [NBP1-83908] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Applications for LZTS1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200-1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LZTS1

LZTS1, also known as leucine zipper putative tumor suppressor 1, consists of seven isoforms of sizes 66.6 kDa, 63.8 kDa, 62.9 kDa, 59.8 kDa, 55.6 kDa, 22.5 kDa, and 8.6 kDa and is involved in suppressing tumors by regulating cell growth. Diseases and disorder such as breast cancer, ovarian cancer, melanoma, esophagitis, squamous cell carcinoma, lung cancer, and prostatitis are being researched with the protein. The protein interacts in transcription, gene expression, and RNA Polymerase III transcription initiation pathways with CDK1, GTF3A, CDC25C, EEF1G, and GTF3C1.

Alternate Names

F37, F37/esophageal cancer-related gene-coding leucine-zipper motifFez1, FEZ1leucine zipper putative tumor suppressor 1, leucine zipper, putative tumor suppressor 1

Gene Symbol

LZTS1

Additional LZTS1 Products

Product Documents for LZTS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for LZTS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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