LZTS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-17195

Novus Biologicals, part of Bio-Techne
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NBP2-17195
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Bovine (90%), Rat (92%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all LZTS1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human LZTS1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%).

Localization

Cytoplasm (By similarity); Cell membrane (By similarity); Cell projection; dendritic spine (By similarity); Cell junction; synapse; postsynaptic cell membrane; postsynaptic density (By similarity); synapse (By similarity)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

67 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for LZTS1 Antibody

Western Blot: LZTS1 Antibody [NBP2-17195]

Western Blot: LZTS1 Antibody [NBP2-17195]

Western Blot: LZTS1 Antibody [NBP2-17195] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: LZTS1 Antibody [NBP2-17195]

Immunohistochemistry-Paraffin: LZTS1 Antibody [NBP2-17195]

Immunohistochemistry-Paraffin: LZTS1 Antibody [NBP2-17195] - Human breast cancer, using FEZ1 antibody at 1:250 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for LZTS1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: LZTS1

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq]

Alternate Names

F37, F37/esophageal cancer-related gene-coding leucine-zipper motifFez1, FEZ1leucine zipper putative tumor suppressor 1, leucine zipper, putative tumor suppressor 1

Gene Symbol

LZTS1

UniProt

Q9Y250 (Human)

Additional LZTS1 Products

Product Documents for LZTS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for LZTS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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