Macro H2A.2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00055506-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Macro H2A.2 Antibodies »

Product Specifications

Immunogen

H2AFY2 (NP_061119.1, 1 a.a. - 372 a.a.) full-length human protein. MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEILELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGTKGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPGDGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIGIYVQEMAKLDAK

Specificity

Reacts with H2A histone family, member Y2.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Macro H2A.2 Antibody

Western Blot: Macro H2A.2 Antibody [H00055506-D01P]

Western Blot: Macro H2A.2 Antibody [H00055506-D01P]

Western Blot: Macro H2A.2 Antibody [H00055506-D01P] - Analysis of H2AFY2 expression in transfected 293T cell line by H2AFY2 polyclonal antibody.Lane 1: H2AFY2 transfected lysate(40.10 KDa).Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: Macro H2A.2 Antibody [H00055506-D01P]

Immunocytochemistry/ Immunofluorescence: Macro H2A.2 Antibody [H00055506-D01P]

Immunocytochemistry/Immunofluorescence: Macro H2A.2 Antibody [H00055506-D01P] - Analysis of antibody to H2AFY2 on HeLa cell. Antibody concentration 30 ug/ml.

Applications for Macro H2A.2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Macro H2A.2

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation

Alternate Names

core histone macro-H2A.2, core histone macroH2A2.2, H2A histone family, member Y2, Histone macroH2A2, macroH2A2, mH2A2

Entrez Gene IDs

55506 (Human)

Gene Symbol

MACROH2A2

UniProt

NP_061119.1 (Human)

Additional Macro H2A.2 Products

Product Documents for Macro H2A.2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Macro H2A.2 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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