MafK Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56366

Novus Biologicals, part of Bio-Techne
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NBP2-56366
NBP2-56366-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MafK Antibodies »

Product Summary for MafK Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ITIVKSTELSSTSVPFSAAS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MafK Antibody

Immunocytochemistry/ Immunofluorescence: MafK Antibody [NBP2-56366]

Immunocytochemistry/ Immunofluorescence: MafK Antibody [NBP2-56366]

Immunocytochemistry/Immunofluorescence: MafK Antibody [NBP2-56366] - Staining of human cell line HeLa shows localization to nucleoplasm. Antibody staining is shown in green.

Applications for MafK Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MafK

The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 177000). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM]

Long Name

v-maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog K

Alternate Names

NFE2U

Gene Symbol

MAFK

Additional MafK Products

Product Documents for MafK Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MafK Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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