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MAML1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83025

Novus Biologicals, part of Bio-Techne
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NBP1-83025
NBP1-83025-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MAML1 Antibody

Immunocytochemistry/ Immunofluorescence: MAML1 Antibody [NBP1-83025]

Immunocytochemistry/ Immunofluorescence: MAML1 Antibody [NBP1-83025]

Immunocytochemistry/Immunofluorescence: MAML1 Antibody [NBP1-83025] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: MAML1 Antibody [NBP1-83025]

Immunohistochemistry-Paraffin: MAML1 Antibody [NBP1-83025]

Immunohistochemistry-Paraffin: MAML1 Antibody [NBP1-83025] - Staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.

Applications for MAML1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MAML1

MAML1 is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Alternate Names

FLJ53540, KIAA0200Mam1, Mam-1mastermind homolog, mastermind (drosophila)-like 1, mastermind-like 1 (Drosophila), mastermind-like protein 1

Gene Symbol

MAML1

Additional MAML1 Products

Product Documents for MAML1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MAML1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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