MAP4K2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88584

Novus Biologicals, part of Bio-Techne
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NBP1-88584
NBP1-88584-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MAP4K2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ETDPLNEPWEEEWTLLGKEELSGSLLQSVQEALEERSLTIRSASEFQELDSPDDTMGTIKRAPFLGPLPTDPPAEEPLSSPPGTLPPPPSGPNSSPLLPTAWATMKQRE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MAP4K2 Antibody

Immunocytochemistry/ Immunofluorescence: MAP4K2 Antibody [NBP1-88584]

Immunocytochemistry/ Immunofluorescence: MAP4K2 Antibody [NBP1-88584]

Immunocytochemistry/Immunofluorescence: MAP4K2 Antibody [NBP1-88584] - Immunofluorescent staining of human cell line A-431 shows localization to vesicles.
Immunohistochemistry-Paraffin: MAP4K2 Antibody [NBP1-88584]

Immunohistochemistry-Paraffin: MAP4K2 Antibody [NBP1-88584]

Immunohistochemistry-Paraffin: MAP4K2 Antibody [NBP1-88584] - Staining in human lymph node and liver tissues using anti-MAP4K2 antibody. Corresponding MAP4K2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: MAP4K2 Antibody [NBP1-88584]

Immunohistochemistry-Paraffin: MAP4K2 Antibody [NBP1-88584]

Immunohistochemistry-Paraffin: MAP4K2 Antibody [NBP1-88584] - Staining of human liver shows low expression as expected.
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Applications for MAP4K2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MAP4K2

MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. MAP4K2 can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Long Name

Mitogen-activated protein kinase kinase kinase kinase 2

Alternate Names

GC kinase, MEK kinase kinase 2, MEKKK 2, RAB8IP

Gene Symbol

MAP4K2

Additional MAP4K2 Products

Product Documents for MAP4K2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MAP4K2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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