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MAP4K6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-22990

Novus Biologicals, part of Bio-Techne
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NBP1-22990

Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 775 and 825 of human misshapen-like kinase 1 using the numbering given in entry NP_722549.2 (GeneID 50488).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MAP4K6 Antibody

Western Blot: MAP4K6 Antibody [NBP1-22990] -

Western Blot: MAP4K6 Antibody [NBP1-22990] - Whole cell lysate from HeLa and mouse NIH3T3 cells at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.

Applications for MAP4K6 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MAP4K6

MINK1 (misshapen/NIKs-related kinase 1) is a member of the germinal center kinase (GCK) family that are homologous to the yeast sterile 20 (Ste20) kinases. GCKs function in the activation of the JNK pathway. MINK1 has been found to activate the JNK pathway and may have a role in modulating cytoskeletal organization, cell adhesion, and cell migration during development.

Alternate Names

B55, EC 2.7.11, GCK family kinase MiNK, hMINK, hMINKbeta, MAP4K6EC 2.7.11.1, MAPK/ERK kinase kinase kinase 6, MEK kinase kinase 6, MGC21111, MINKMEKKK 6, Misshapen/NIK-related kinase, misshapen-like kinase 1, misshapen-like kinase 1 (zebrafish), Mitogen-activated protein kinase kinase kinase kinase 6, serine/threonine protein kinase, YSK2, ZC3

Entrez Gene IDs

50488 (Human); 50932 (Mouse)

Gene Symbol

MINK1

UniProt

Additional MAP4K6 Products

Product Documents for MAP4K6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MAP4K6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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