MARCH4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59736

Novus Biologicals, part of Bio-Techne
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NBP1-59736
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all MARCH4 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to MARCH4(membrane-associated ring finger (C3HC4) 4) The peptide sequence was selected form the N terminal of 40241. Peptide sequence GLLKCRCRMLFNDLKVFLLRRPPQAPLPMHGDPQPPGLAANNTLPALGAG. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for MARCH4 Antibody

Western Blot: MARCH4 Antibody [NBP1-59736]

Western Blot: MARCH4 Antibody [NBP1-59736]

Western Blot: MARCH4 Antibody [NBP1-59736] - Titration: 0.2-1 ug/ml, Positive Control: Hela cell lysate.

Applications for MARCH4 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MARCH4

MARCH4 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Alternate Names

EC 6.3.2.-, KIAA1399E3 ubiquitin-protein ligase MARCH4, MARCH-IVMGC104908, membrane-associated ring finger (C3HC4) 4, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, RNF174RING finger protein 174

Gene Symbol

MARCH4

OMIM

NP_065865 (Human)

UniProt

Q9P2E8 (Human)

Additional MARCH4 Products

Product Documents for MARCH4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MARCH4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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