MARCH8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59515

Novus Biologicals, part of Bio-Techne
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NBP1-59515
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all MARCH8 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to MARCH8(membrane-associated ring finger (C3HC4) 8) The peptide sequence was selected from the middle region of 40245. Peptide sequence YVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENKHG. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for MARCH8 Antibody

Western Blot: MARCH8 Antibody [NBP1-59515]

Western Blot: MARCH8 Antibody [NBP1-59515]

Western Blot: MARCH8 Antibody [NBP1-59515] - Human Muscle lysate, concentration 0.2-1 ug/ml.

Applications for MARCH8 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MARCH8

MARCH8 is an E3 ubiquitin-protein ligase that may regulate immune responses by promoting ubiquitination of MHC-II and CD86, which leads to their subsequent endocytosis and lysosomal degradation. It may also promote ubiquitination and endocytosis of TFRC and FAS. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Long Name

Membrane Associated Ring Finger (C3HC4) 8

Alternate Names

c-MIR, MARCH-VIII, RNF178

Gene Symbol

MARCHF8

UniProt

Q5T0T0

Additional MARCH8 Products

Product Documents for MARCH8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MARCH8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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