Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all Matrin 3 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residues 475 and 500 of human Matrin 3 using the numbering given in entry NP_061322.2 (GeneID 9782).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Matrin 3 Antibody

Immunohistochemistry: Matrin 3 Antibody [NB100-1559]

Immunohistochemistry: Matrin 3 Antibody [NB100-1559]

Immunohistochemistry: Matrin 3 Antibody [NB100-1559] - Sample: FFPE section of human laryengeal squamous cell carcinoma (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti- Matrin 3 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunoprecipitation: Matrin 3 Antibody [NB100-1559]

Immunoprecipitation: Matrin 3 Antibody [NB100-1559]

Immunoprecipitation: Matrin 3 Antibody [NB100-1559] - Detection of Human Matrin 3 by Western Blot after Immunoprecipitation. Samples: Whole cell lysate (1 mg for IP, 1/4 of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-Matrin 3 antibody NB100-1559 used for IP at 3 mcg/mg lysate. Matrin 3 was also immunoprecipitated using rabbit anti-Matrin 3 NB100-1560 and another Matrin 3 Ab at 3 mcg/mg lysate. Detection: Chemiluminescence with an exposure time of 3 seconds.

Applications for Matrin 3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000-1:5000

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

1-4 ug/mg of lysate
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Matrin 3

Matrin 3 is a nuclear matrix protein that has been observed to mediate multiple cellular processes. Matrin 3 can function to withhold defective RNAs within the nucleus by anchoring them to the nuclear matrix and modulate the promoter activity of genes proximal to matrix/scaffold attachment region (MAR/SAR). Matrin 3 has also been demonstrated to be the main PKA substrate following NMDA receptor activation in NMDA-induced neuronal cell death. Alternate names for Matrin 3 include MATR3, MGC9105, KIAA0723, DKFZp686K0542, and DKFZp686K23100.

Alternate Names

distal 2, DKFZp686K0542, DKFZp686K23100, matrin 3, matrin-3, vocal cord and pharyngeal weakness with distal myopathy

Entrez Gene IDs

9782 (Human); 17184 (Mouse)

Gene Symbol

MATR3

UniProt

NP_061322.2 (Human)

Additional Matrin 3 Products

Product Documents for Matrin 3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Matrin 3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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