MBL Antibody (11F11) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-05078

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 11F11

Format

BSA Free

Concentration

1.0 mg/ml

View all MBL Antibodies »

Product Specifications

Immunogen

MBL purified from human donor plasma and adsorbed onto aluminum hydroxide.

Epitope

Not determined (presumably reacts with the carbohydrate recognition domain)

Reactivity Notes

Reacts with Human and Rat.

Specificity

Mannan-binding lectin

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for MBL Antibody (11F11) - BSA Free

Application
Recommended Usage

ELISA

1:2000

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM Phosphate (pH 7.4) and 0.5M NaCl

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MBL

Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collections, showing calcium-dependent binding to certain sugars (1). It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum (2)

Long Name

Mannose Binding Lectin

Alternate Names

COLEC1, Collectin-1, MBL2, MBL2D, MBP1

Gene Symbol

MBL2

Additional MBL Products

Product Documents for MBL Antibody (11F11) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MBL Antibody (11F11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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