MCCC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38930

Novus Biologicals, part of Bio-Techne
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NBP2-38930
NBP2-38930-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MCCC2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LPCIYLVDSGGAYLPRQADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MCCC2 Antibody

Immunohistochemistry-Paraffin: MCCC2 Antibody [NBP2-38930]

Immunohistochemistry-Paraffin: MCCC2 Antibody [NBP2-38930]

Immunohistochemistry-Paraffin: MCCC2 Antibody [NBP2-38930] - Staining in human kidney and skeletal muscle tissues using anti-MCCC2 antibody. Corresponding MCCC2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: MCCC2 Antibody [NBP2-38930]

Immunohistochemistry-Paraffin: MCCC2 Antibody [NBP2-38930]

Immunohistochemistry-Paraffin: MCCC2 Antibody [NBP2-38930] - Staining of human kidney, liver, skeletal muscle and skin using Anti-MCCC2 antibody NBP2-38930 (A) shows similar protein distribution across tissues to independent antibody NBP2-38403 (B).
Western Blot: MCCC2 Antibody [NBP2-38930]

Western Blot: MCCC2 Antibody [NBP2-38930]

Western Blot: MCCC2 Antibody [NBP2-38930] - Analysis using Anti-MCCC2 antibody NBP2-38930 (A) shows similar pattern to independent antibody NBP1-82794 (B).
View 5 more images

Applications for MCCC2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MCCC2

MCCC2 encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Alternate Names

3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta, MCCase subunit beta, MCCBEC 6.4.1.4, methylcrotonoyl-CoA carboxylase 2 (beta), methylcrotonoyl-Coenzyme A carboxylase 2 (beta), mitochondrial, non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase

Gene Symbol

MCCC2

UniProt

Q9HCC0 (Human)

Additional MCCC2 Products

Product Documents for MCCC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MCCC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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