MCG10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55526

Novus Biologicals, part of Bio-Techne
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NBP2-55526
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MCG10 Antibodies »

Product Summary for MCG10 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MCG10 Antibody

Western Blot: MCG10 Antibody [NBP2-55526]

Western Blot: MCG10 Antibody [NBP2-55526]

Western Blot: MCG10 Antibody [NBP2-55526] - Western blot analysis in human cell line RT-4 and human cell line U-251 MG.
Immunocytochemistry/ Immunofluorescence: MCG10 Antibody [NBP2-55526]

Immunocytochemistry/ Immunofluorescence: MCG10 Antibody [NBP2-55526]

Immunocytochemistry/Immunofluorescence: MCG10 Antibody [NBP2-55526] - Staining of human cell line MCF7 shows localization to cytosol.

Applications for MCG10 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MCG10

MCG10 encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.

Alternate Names

alpha-CP4, alphaCP-4 protein, CBP, LIP4, LYST-interacting protein, MCG10, poly(rC) binding protein 4, poly(rC)-binding protein 4, RNA binding protein MCG10

Gene Symbol

PCBP4

Additional MCG10 Products

Product Documents for MCG10 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MCG10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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