MCM6 Antibody (S02-2I2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19486

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19486-100ul
NBP3-19486-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S02-2I2

Concentration

0.3 mg/ml

View all MCM6 Antibodies »

Product Specifications

Immunogen

Recombinant protein of human MCM6 (Uniprot # Q14566)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

93 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MCM6 Antibody (S02-2I2)

Western Blot: MCM6 Antibody (S02-2I2) [NBP3-19486]

Western Blot: MCM6 Antibody (S02-2I2) [NBP3-19486]

Western Blot: MCM6 Antibody (S02-2I2) [NBP3-19486] - Western blot detection of MCM6 in Jurkat cell lysates using NBP3-19486 (1:1000 diluted). Predicted band size: 93kDa. Observed band size: 93kDa.
Immunocytochemistry/ Immunofluorescence: MCM6 Antibody (S02-2I2) [NBP3-19486]

Immunocytochemistry/ Immunofluorescence: MCM6 Antibody (S02-2I2) [NBP3-19486]

Immunocytochemistry/Immunofluorescence: MCM6 Antibody (S02-2I2) [NBP3-19486] - Immunofluorescence of MCM6 (green) in Hela using NBP3-19486 at dilution 1/5, and DAPI (blue)
Immunohistochemistry-Paraffin: MCM6 Antibody (S02-2I2) [NBP3-19486]

Immunohistochemistry-Paraffin: MCM6 Antibody (S02-2I2) [NBP3-19486]

Immunohistochemistry-Paraffin: MCM6 Antibody (S02-2I2) [NBP3-19486] - Immunohistochemistry of MCM6 in paraffin-embedded Human tonsil using NBP3-19486 at dilution 1/50

Applications for MCM6 Antibody (S02-2I2)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/50

Immunohistochemistry

1/500

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MCM6

MCM6 is encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Alternate Names

DNA replication licensing factor MCM6, EC 3.6.4.12, MCG40308, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S.cerevisiae), minichromosome maintenance complex component 6, minichromosome maintenance deficient (mis5, S. pombe) 6, minichromosome maintenance deficient 6 homolog, minichromosome maintenance deficient 6 homolog (S. cerevisiae), Mis5, MIS5 homolog, p105MCM

Gene Symbol

MCM6

Additional MCM6 Products

Product Documents for MCM6 Antibody (S02-2I2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MCM6 Antibody (S02-2I2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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