MD-1/LY86 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56700

Novus Biologicals, part of Bio-Techne
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NB100-56700
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all MD-1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a KLH-conjugated synthetic peptide corresponding to amino acids 112-125 of human MD-1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MD-1/LY86 Antibody

Western Blot: MD-1/LY86 Antibody [NB100-56700]

Western Blot: MD-1/LY86 Antibody [NB100-56700]

Western Blot: MD-1/LY86 Antibody [NB100-56700] - Analysis of MD-1 in Ramos lysate using MD-1 antibody at 2 ug/ml.
Immunohistochemistry-Paraffin: MD-1/LY86 Antibody [NB100-56700]

Immunohistochemistry-Paraffin: MD-1/LY86 Antibody [NB100-56700]

Immunohistochemistry-Paraffin: MD-1/LY86 Antibody [NB100-56700] - Analysis of human spleen using MD-1 antibody at 10 ug/ml.

Applications for MD-1/LY86 Antibody

Application
Recommended Usage

Western Blot

2 ug/ml
Application Notes
In Ramos, a 25 kDa band is observed.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MD-1

Mammalian MD-1 is a homolog of Chicken MD-1, which was previously isolated as a v-myb-regulated gene, since its transcription increases rapidly after v-myb induction. MD-1 is associated at the cell surface with RP105. RP105 is a leucine-rich repaeat (LRR) molecule that is expressed on B-lymphocytes. It was first identified by a mAb that protects spleen B cells from irradiation-induced apoptosis (2). LRR proteins, such as Toll receptors, have a role in innate immunity. MD-1 does not have any homology to other molecules. MD-1 when expressed alone behaves as a secretory protein. Expression of MD-1 in a cell increases the expression of RP105.

Long Name

Myeloid Differentiation Protein 1/Lymphocyte Antigen 86

Alternate Names

LY86, MD1

Entrez Gene IDs

9450 (Human); 17084 (Mouse)

Gene Symbol

LY86

UniProt

O95711

Additional MD-1 Products

Product Documents for MD-1/LY86 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MD-1/LY86 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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