MDR1/ABCB1 Antibody (6G11C12) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37294

Novus Biologicals, part of Bio-Techne
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NBP2-37294
NBP2-37294-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 6G11C12

Format

BSA Free

Concentration

1 mg/ml

View all MDR1/ABCB1 Antibodies »

Product Summary for MDR1/ABCB1 Antibody (6G11C12) - BSA Free

Immunogen

Purified recombinant fragment of human MDR1/ABCB1 (AA: 632-693) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

141.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MDR1/ABCB1 Antibody (6G11C12) - BSA Free

Western Blot: MDR1/ABCB1 Antibody (6G11C12)BSA Free [NBP2-37294]

Western Blot: MDR1/ABCB1 Antibody (6G11C12)BSA Free [NBP2-37294]

Western Blot: MDR1/ABCB1 Antibody (6G11C12) [NBP2-37294] - Analysis using ABCB1 mAb against HEK293 (1) and ABCB1 (AA: 632-693)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot: MDR1/ABCB1 Antibody (6G11C12)BSA Free [NBP2-37294]

Western Blot: MDR1/ABCB1 Antibody (6G11C12)BSA Free [NBP2-37294]

Western Blot: MDR1/ABCB1 Antibody (6G11C12) [NBP2-37294] - Analysis using ABCB1 mAb against human ABCB1 (AA: 632-693) recombinant protein. (Expected MW is 32.4 kDa).
ELISA: MDR1/ABCB1 Antibody (6G11C12) - BSA Free [NBP2-37294]

ELISA: MDR1/ABCB1 Antibody (6G11C12) - BSA Free [NBP2-37294]

ELISA: MDR1/ABCB1 Antibody (6G11C12) [NBP2-37294] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);

Applications for MDR1/ABCB1 Antibody (6G11C12) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MDR1/ABCB1

MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). MDR1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. (provided by RefSeq)

Long Name

ATP-binding Cassette, Sub-family B (MDR/TAP), Member 1B

Alternate Names

ABC20, ABCB1, ABCB1B, CD243, CLCS, GP170, IBD13, PGY1

Gene Symbol

ABCB1

Additional MDR1/ABCB1 Products

Product Documents for MDR1/ABCB1 Antibody (6G11C12) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MDR1/ABCB1 Antibody (6G11C12) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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