MDR3/ABCB4 Antibody (P3II-26)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21455

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # P3II-26

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MDR3/ABCB4 Antibodies »

Product Summary for MDR3/ABCB4 Antibody (P3II-26)

Immunogen

Selected after immunization with a fusion protein of Gluthathione S Transferase and a fragment of MDR3/ABCB4 (amino acids 629-692)

Specificity

Reacts with internal epitope of MDR3/ABCB4. Does not cross-react with the human MDR1 P-gp.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for MDR3/ABCB4 Antibody (P3II-26)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:20-1:50

Immunohistochemistry-Frozen

1:2
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, 0.1% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: MDR3/ABCB4

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. (provided by RefSeq)

Long Name

Multiple Drug Resistance 3

Alternate Names

ABC21, ABCB4, GBD1, PFIC-3, PGY3

Gene Symbol

ABCB4

Additional MDR3/ABCB4 Products

Product Documents for MDR3/ABCB4 Antibody (P3II-26)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MDR3/ABCB4 Antibody (P3II-26)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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