MDR3/ABCB4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-30876

Novus Biologicals, part of Bio-Techne
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NBP2-30876
NBP2-30876-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MDR3/ABCB4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LEAAKNGTAWRPTSAEGDFELGISSKQKRKKTKTVKMIGVLTLFRYSDWQD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MDR3/ABCB4 Antibody

Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876]

Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876]

Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876] - Staining of human skeletal muscle shows no positivity in myocytes as exected.
Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876]

Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876]

Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876] - Staining of human cerebral cortex shows no positivity in neurons as expected.
Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876]

Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876]

Immunohistochemistry-Paraffin: MDR3/ABCB4 Antibody [NBP2-30876] - Staining of human liver shows weak to moderate membranous positivity in bile duct cells.
View 1 more images

Applications for MDR3/ABCB4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MDR3/ABCB4

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. (provided by RefSeq)

Long Name

Multiple Drug Resistance 3

Alternate Names

ABC21, ABCB4, GBD1, PFIC-3, PGY3

Gene Symbol

ABCB4

UniProt

P21439 (Human)

Additional MDR3/ABCB4 Products

Product Documents for MDR3/ABCB4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MDR3/ABCB4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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